Improvement of ε-Poly-l-lysine Production by Co-Culture Fermentation Strategy

Efficacy of ε-Poly-L-lysine as an Antibacterial Additive for Platelets Stored at Room Temperature

A natural preservative ε-poly-L-lysine: fermentative production and applications in food industry

ε-Poly-L-lysine (ε-PL) is a homopolymer linked by the peptide bond between the carboxylic and the epsilon amino group of adjacent lysine molecules. It is naturally occurring, water soluble, biodegradable, edible and nontoxic towards humans and environment. ε-PL shows a wide range of antimicrobial activity and is stable at high temperatures. This review focuses on various ε-PL producing strains,...

Efficient production of ε-poly-L-lysine by Streptomyces ahygroscopicus using one-stage pH control fed-batch fermentation coupled with nutrient feeding.

ε-Poly-L-lysine (ε-PL) is a homopolymer of L-lysine molecules connected between the ε amino and alpha carboxyl groups. This polymer is currently used as a natural preservative in food. Insufficient biomass is a major problem in ε-PL fermentation. Here, to improve cell growth and ε-PL productivity, various nitrogen-rich nutrients were supplemented into flask cultures after 16 h cultivation, mark...

Enhancement of ε-poly-l-lysine (ε-PL) production by a novel producer Bacillus cereus using metabolic precursors and glucose feeding

Epsilon poly-L-lysine (ε-PL) is a homo-biopolymer with approximately 25-30 L-lysine residues. It is a promising natural biopolymer widely used in food and pharmaceutical industry. The present work reports enhanced production of ε-PL with a novel producer Bacillus cereus using amino acids and TCA cycle intermediates in the fermentation medium. Among the various amino acids and TCA cycle intermed...

Efficient Production of Live Offspring from Mouse Oocytes Vitrified with a Novel Cryoprotective Agent, Carboxylated ε-poly-L-lysine

In cryopreservation of mammalian germ cells, unfertilized oocytes are one of the most available stages because these cryopreserved oocytes can be used for assisted reproductive technologies, including in vitro fertilization (IVF) and intracytoplasmic sperm injection. However, it has been generally reported that the fertility and developmental ability of the oocytes are reduced by cryopreservati...